NeuBrain Revive promotes anti-inflammatory and detoxification support using multiple compounds that work synergistically to leverage the body’s innate ability to self-heal, including:
N-acetyl cysteine raises levels of glutathione, one of the most powerful antioxidants in the body. It assists detoxification in the brain, and can help reduce irritability and addiction cravings.
Focus on Mechanisms
N-acetyl cysteine is a powerful antioxidant and anti-inflammatory agent of the body, which has both direct effects as well as raising levels of glutathione, arguably the most powerful antioxidant in the body. This enables it to perform multiple actions, including clear the body of toxins such as lead and defend from infections.
Effects of Brain
Through its antioxidant functions, it has been found to lower inflammation in the brain. By lowering inflammation, some studies suggest it could support cognition, particularly if the brain is under stress.
Effects on Addictions
N-acetyl cysteine appears to support the brain in overcoming addictions. It has been studied in a variety of addictive states, and provides support in overcoming cigarette smoking and even stronger forms of addiction. Though naturally occuring in the body, it’s powerful enough that it’s still commonly used today in hospitals in certain situations of drug overdoses.
The main form of vitamin B12 in the body, methylcobalamin plays multiple roles in brain cells, including detoxification and DNA synthesis. It is best known for its roles in energy metabolism and it also supports cognition.
Lowering Inflammation and Effects
Methylcobalamin lowers inflammation in cells. New studies suggest this will indirectly support healthy cognition, by removing the inflammation linked with different illnesses that affect memory. The later effects of lowering inflammation can include lowering pain. In combination with folate, it’s also believed to positively affect mood.
DNA Synthesis and Ability to Absorb Light
Methylcobalamin also plays an important role in the synthesis of new DNA and how a gene is expressed, or genetic expression. Recently, methylcobalamin has also been discovered to be a “photoreceptor,” which means it can absorb light. Interestingly, this implies that light absorption activates methylcobalamin and influences gene expression in cells.
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Diet, nutrition and the ageing brain: current evidence and new directions.
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4. Cheng et al. Cobalamin’s (Vitamin B12) Surprising Function as a Photoreceptor ,Trends Biochem Sci. 2016 Aug; 41(8): 647–650.
5. Cheng et al. Mol Microbiol. 2014 Feb; 91(4): 649–664. Vitamin B12 regulates photosystem gene expression via the CrtJ antirepressor AerR in Rhodobacter capsulatus
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Quercetin is a “bioflavonoid,” a naturally occurring antioxidant found throughout many substances in nature. These compounds, as part of a larger family of compounds known as “polyphenols,” have been studied to have an exceptionally broad array of positive of effects for the brain and body, including lowering inflammation, protecting from cancer, supporting vascular health, lowering pain, and more. Quercetin functions at multiple locations in the cell, from the DNA to the outer membranes.
One reason that quercetin has such a broad range of effects is that it can work at multiple cell levels. First, quercetin has the ability interact and incorporate itself into the outer layer of the cell, the cell membrane. At the opposite end of the spectrum, with regards to preventing cancer, it appears quercetin has the ability to directly bond with DNA.
Quercetin has been shown to protect neurons from various types of stressors. As a result, it is hypothesized to protect from neurodegenerative illnesses such as Alzheimer’s. One study in animals actually showed that cognitive decline from severe inflammation can be reversed with flavonoids such as quercetin. Quercetin is also being studied for treatment of depression.
Protective Effect of Flavonoids against Aging- and Lipopolysaccharide-Induced Cognitive Impairment in Mice. Pharmacology 2003;69:59–67
Curcumin is a potent antioxidant found naturally in turmeric and ginger. Its effects on the brain include reducing inflammation as well as improving mood. Like quercetin, it has an extremely broad range of activities, and has been shown to reduce pain, protect from multiple cancers and Alzheimer’s, treat inflammatory conditions, and more.
Curcumin is well studied for its effects of preventing cognitive decline.
Multiple studies have shown its ability to improve mood, specifically reducing both depression and anxiety. Along with reducing inflammation, it has unique mechanisms to do this, including raising natural synthesis of omega fatty acids necessary for neuronal growth. Another study found it protects dendrite length, which are the parts of the neurons which make connections to other neurons.
Other interesting effects of curcumin found in animal studies is increasing fine motor abilities (such as speed of hand movement) and spatial memory. It also protects the brain in times of oxygen and sleep deprivation.